| PLAYER | YEAR | TEAM | G | IP | H | ER | BB | SO | ERA | W | L | PCT | SV | BSV | GS | CG | SHO | WHIP |
| Eaton, Adam | 2001 | HBK | 27 | 136.7 | 171 | 99 | 84 | 64 | 6.52 | 5 | 14 | 0.263 | 0 | 0 | 26 | 0 | 0 | 1.87 |
| Eaton, Adam | 2002 | HBK | 15 | 101.0 | 116 | 61 | 26 | 70 | 5.44 | 7 | 6 | 0.538 | 0 | 0 | 15 | 0 | 0 | 1.41 |
| Eaton, Adam | 2004 | PHI | 4 | 11.7 | 24 | 17 | 8 | 5 | 13.11 | 0 | 2 | 0.000 | 0 | 0 | 4 | 0 | 0 | 2.74 |
| Eaton, Adam | 2005 | HIL | 32 | 176.0 | 243 | 128 | 65 | 126 | 6.55 | 7 | 12 | 0.368 | 0 | 0 | 32 | 0 | 0 | 1.75 |
| Eaton, Adam | 2006 | HBK | 2 | 10.3 | 18 | 8 | 2 | 10 | 6.97 | 1 | 0 | 1.000 | 0 | 0 | 2 | 0 | 0 | 1.94 |
| CAREER | 80 | 435.7 | 572 | 313 | 185 | 275 | 6.47 | 20 | 34 | 0.370 | 0 | 0 | 79 | 0 | 0 | 1.74 | ||
| Eckersley, Dennis | 1991 | VAN | 64 | 128.0 | 79 | 16 | 20 | 120 | 1.13 | 15 | 4 | 0.789 | 10 | 0 | 0 | 0 | 0.77 | |
| Eckersley, Dennis | 1992 | VAN | 97 | 163.0 | 124 | 38 | 25 | 222 | 2.10 | 10 | 5 | 0.667 | 19 | 0 | 0 | 0 | 0.91 | |
| Eckersley, Dennis | 1993 | VAN | 37 | 65.7 | 71 | 27 | 15 | 65 | 3.70 | 5 | 4 | 0.556 | 9 | 5 | 0 | 0 | 0 | 1.31 |
| Eckersley, Dennis | 1996 | TOL | 63 | 95.7 | 148 | 70 | 51 | 100 | 6.59 | 6 | 11 | 0.353 | 5 | 10 | 0 | 0 | 0 | 2.08 |
| Eckersley, Dennis | 1997 | TOL | 55 | 61.0 | 95 | 51 | 16 | 42 | 7.52 | 3 | 8 | 0.273 | 25 | 0 | 0 | 0 | 1.82 | |
| Eckersley, Dennis | 1998 | PHI | 19 | 26.0 | 31 | 20 | 7 | 22 | 6.92 | 2 | 1 | 0.667 | 8 | 3 | 0 | 0 | 0 | 1.46 |
| Eckersley, Dennis | 1998 | ARK | 13 | 18.7 | 15 | 8 | 3 | 8 | 3.86 | 0 | 2 | 0.000 | 2 | 0 | 0 | 0 | 0 | 0.96 |
| CAREER | 348 | 558.0 | 563 | 230 | 137 | 579 | 3.71 | 41 | 35 | 0.539 | 78 | 18 | 0 | 0 | 0 | 1.25 | ||
| Edens, Tom | 1993 | COL | 3 | 3.0 | 5 | 1 | 1 | 3 | 3.00 | 0 | 0 | #DIV/0! | 0 | 0 | 0 | 0 | 0 | 2.00 |
| CAREER | 3 | 3.0 | 5 | 1 | 1 | 3 | 3.00 | 0 | 0 | #DIV/0! | 0 | 0 | 0 | 0 | 0 | 2.00 | ||
| Edgin, Josh | 2013 | BKC | 59 | 64.0 | 71 | 50 | 33 | 70 | 7.03 | 2 | 8 | 0.200 | 1 | 6 | 0 | 0 | 0 | 1.63 |
| CAREER | 59 | 64.0 | 71 | 50 | 33 | 70 | 7.03 | 2 | 8 | 0.200 | 1 | 6 | 0 | 0 | 0 | 1.63 | ||
| Eichhorn, Mark | 1992 | ARK | 46 | 106.7 | 83 | 20 | 15 | 72 | 1.69 | 11 | 4 | 0.733 | 1 | 0 | 0 | 0 | 0.92 | |
| Eichhorn, Mark | 1994 | CHA | 53 | 202.0 | 305 | 137 | 83 | 141 | 6.10 | 4 | 4 | 0.500 | 1 | 0 | 0 | 0 | 0 | 1.92 |
| CAREER | 99 | 308.7 | 388 | 157 | 98 | 213 | 4.58 | 15 | 8 | 0.652 | 2 | 0 | 0 | 0 | 0 | 1.57 | ||
| Eischen, Joey | 1997 | CAR | 15 | 23.3 | 26 | 10 | 15 | 18 | 3.86 | 1 | 1 | 0.500 | 0 | 0 | 0 | 0 | 1.76 | |
| Eischen, Joey | 2003 | STP | 61 | 77.3 | 66 | 30 | 26 | 63 | 3.49 | 2 | 3 | 0.400 | 0 | 2 | 0 | 0 | 0 | 1.19 |
| CAREER | 76 | 100.7 | 92 | 40 | 41 | 81 | 3.58 | 3 | 4 | 0.429 | 0 | 2 | 0 | 0 | 0 | 1.32 | ||
| Elarton, Scott | 2000 | HAW | 25 | 144.0 | 166 | 77 | 41 | 105 | 4.81 | 6 | 6 | 0.500 | 0 | 0 | 25 | 2 | 0 | 1.44 |
| Elarton, Scott | 2001 | HBK | 31 | 187.7 | 202 | 116 | 116 | 109 | 5.56 | 8 | 10 | 0.444 | 0 | 0 | 31 | 1 | 0 | 1.69 |
| CAREER | 56 | 331.7 | 368 | 193 | 157 | 214 | 5.24 | 14 | 16 | 0.467 | 0 | 0 | 56 | 3 | 0 | 1.58 | ||
| Elbert, Scott | 2012 | ARK | 55 | 74.3 | 86 | 34 | 22 | 76 | 4.12 | 5 | 2 | 0.714 | 0 | 1 | 0 | 0 | 0 | 1.45 |
| Elbert, Scott | 2013 | BRI | 62 | 58.0 | 64 | 23 | 24 | 62 | 3.57 | 2 | 2 | 0.500 | 1 | 3 | 0 | 0 | 0 | 1.52 |
| CAREER | 117 | 132.3 | 150 | 57 | 46 | 138 | 3.88 | 7 | 4 | 0.636 | 1 | 4 | 0 | 0 | 0 | 1.48 | ||
| Eldred, Cal | 1993 | AUS | 32 | 227.0 | 213 | 69 | 56 | 126 | 2.74 | 17 | 6 | 0.739 | 0 | 0 | 32 | 16 | 5 | 1.19 |
| Eldred, Cal | 1997 | LIS | 27 | 167.7 | 167 | 77 | 79 | 86 | 4.13 | 15 | 5 | 0.750 | 0 | 0 | 27 | 2 | 2 | 1.47 |
| Eldred, Cal | 1998 | AUS | 2 | 2.7 | 8 | 7 | 0 | 3 | 23.63 | 0 | 1 | 0.000 | 0 | 0 | 1 | 0 | 0 | 3.00 |
| Eldred, Cal | 2001 | PHX | 34 | 194.7 | 178 | 111 | 89 | 138 | 5.13 | 13 | 7 | 0.650 | 0 | 0 | 32 | 0 | 0 | 1.37 |
| Eldred, Cal | 2005 | TIJ | 8 | 9.3 | 20 | 12 | 7 | 7 | 11.57 | 2 | 1 | 0.667 | 0 | 2 | 0 | 0 | 0 | 2.89 |
| Eldred, Cal | 2006 | WWD | 14 | 16.7 | 23 | 15 | 9 | 19 | 8.10 | 3 | 1 | 0.750 | 1 | 1 | 0 | 0 | 0 | 1.92 |
| CAREER | 117 | 618.0 | 609 | 291 | 240 | 379 | 4.24 | 50 | 21 | 0.704 | 1 | 3 | 92 | 18 | 7 | 1.37 | ||
| Embree, Alan | 1998 | AUS | 76 | 72.3 | 64 | 34 | 41 | 72 | 4.23 | 4 | 3 | 0.571 | 0 | 0 | 0 | 0 | 0 | 1.45 |
| Embree, Alan | 1999 | HAW | 28 | 26.3 | 24 | 14 | 21 | 29 | 4.78 | 2 | 3 | 0.400 | 2 | 0 | 0 | 0 | 0 | 1.71 |
| Embree, Alan | 2000 | HIL | 104 | 140.0 | 144 | 98 | 120 | 131 | 6.30 | 6 | 10 | 0.375 | 5 | 7 | 0 | 0 | 0 | 1.89 |
| Embree, Alan | 2003 | PHI | 47 | 57.0 | 40 | 14 | 20 | 71 | 2.21 | 3 | 2 | 0.600 | 3 | 4 | 0 | 0 | 0 | 1.05 |
| Embree, Alan | 2005 | TIJ | 10 | 13.0 | 18 | 9 | 1 | 12 | 6.23 | 0 | 0 | #DIV/0! | 0 | 0 | 0 | 0 | 0 | 1.46 |
| Embree, Alan | 2007 | VAN | 32 | 33.3 | 33 | 15 | 11 | 30 | 4.05 | 2 | 0 | 1.000 | 0 | 0 | 0 | 0 | 0 | 1.32 |
| CAREER | 297 | 342.0 | 323 | 184 | 214 | 345 | 4.84 | 17 | 18 | 0.486 | 10 | 11 | 0 | 0 | 0 | 1.57 | ||
| Enright, Barry | 2011 | NJ | 16 | 81.3 | 104 | 61 | 33 | 35 | 6.75 | 5 | 8 | 0.385 | 0 | 0 | 16 | 0 | 0 | 1.68 |
| CAREER | 16 | 81.3 | 104 | 61 | 33 | 35 | 6.75 | 5 | 8 | 0.385 | 0 | 0 | 16 | 0 | 0 | 1.68 | ||
| Eovaldi, Nathan | 2013 | SCS | 9 | 23.3 | 29 | 13 | 8 | 18 | 5.01 | 2 | 1 | 0.667 | 0 | 0 | 1 | 0 | 0 | 1.59 |
| Eovaldi, Nathan | 2014 | SCS | 31 | 169.3 | 168 | 69 | 71 | 105 | 3.67 | 8 | 12 | 0.400 | 0 | 0 | 23 | 1 | 0 | 1.41 |
| CAREER | 40 | 192.7 | 197 | 82 | 79 | 123 | 3.83 | 10 | 13 | 0.435 | 0 | 0 | 24 | 1 | 0 | 1.43 | ||
| Erickson, Scott | 1992 | AUS | 32 | 196.0 | 231 | 83 | 80 | 123 | 3.81 | 13 | 10 | 0.565 | 0 | 0 | 32 | 3 | 1.59 | |
| Erickson, Scott | 1993 | CHA | 32 | 178.0 | 220 | 116 | 96 | 87 | 5.87 | 6 | 17 | 0.261 | 0 | 0 | 32 | 5 | 0 | 1.78 |
| Erickson, Scott | 1997 | CAR | 4 | 19.0 | 30 | 17 | 10 | 8 | 8.05 | 1 | 1 | 0.500 | 0 | 3 | 0 | 0 | 2.11 | |
| Erickson, Scott | 1998 | CAR | 32 | 215.3 | 258 | 118 | 61 | 122 | 4.93 | 9 | 13 | 0.409 | 0 | 0 | 32 | 6 | 1 | 1.48 |
| Erickson, Scott | 1999 | HAW | 4 | 23.3 | 43 | 20 | 7 | 12 | 7.71 | 0 | 3 | 0.000 | 0 | 0 | 4 | 1 | 0 | 2.14 |
| Erickson, Scott | 1999 | PHI | 19 | 142.0 | 160 | 64 | 54 | 91 | 4.06 | 8 | 8 | 0.500 | 0 | 0 | 19 | 3 | 0 | 1.51 |
| Erickson, Scott | 2000 | HON | 33 | 181.3 | 210 | 98 | 74 | 73 | 4.86 | 8 | 12 | 0.400 | 0 | 0 | 32 | 2 | 1 | 1.57 |
| CAREER | 156 | 955.0 | 1152 | 516 | 382 | 516 | 4.86 | 45 | 64 | 0.413 | 0 | 0 | 154 | 20 | 2 | 1.61 | ||
| Escobar, Kelvim | 1999 | VAN | 30 | 182.3 | 170 | 82 | 92 | 148 | 4.05 | 17 | 8 | 0.680 | 0 | 0 | 30 | 1 | 0 | 1.44 |
| Escobar, Kelvim | 2002 | HBK | 30 | 167.0 | 143 | 88 | 72 | 145 | 4.74 | 14 | 9 | 0.609 | 0 | 0 | 30 | 0 | 0 | 1.29 |
| Escobar, Kelvim | 2003 | TIJ | 1 | 1.0 | 3 | 1 | 0 | 2 | 9.00 | 0 | 0 | #DIV/0! | 0 | 0 | 0 | 0 | 0 | 3.00 |
| Escobar, Kelvim | 2003 | HAR | 3 | 4.7 | 3 | 0 | 4 | 2 | 0.00 | 0 | 0 | #DIV/0! | 0 | 0 | 0 | 0 | 0 | 1.50 |
| Escobar, Kelvim | 2004 | HAR | 70 | 181.3 | 204 | 106 | 87 | 134 | 5.26 | 3 | 2 | 0.600 | 0 | 0 | 0 | 0 | 0 | 1.60 |
| Escobar, Kelvim | 2005 | LV | 35 | 196.3 | 210 | 106 | 95 | 182 | 4.86 | 10 | 14 | 0.417 | 0 | 0 | 32 | 0 | 0 | 1.55 |
| Escobar, Kelvim | 2006 | DC | 1 | 3.3 | 3 | 2 | 0 | 3 | 5.40 | 0 | 0 | #DIV/0! | 0 | 0 | 0 | 0 | 0 | 0.90 |
| Escobar, Kelvim | 2007 | DC | 32 | 187.3 | 234 | 112 | 56 | 143 | 5.38 | 12 | 9 | 0.571 | 0 | 0 | 32 | 1 | 1 | 1.55 |
| Escobar, Kelvim | 2008 | DC | 33 | 222.7 | 230 | 102 | 82 | 202 | 4.12 | 16 | 12 | 0.571 | 0 | 0 | 33 | 3 | 1 | 1.40 |
| CAREER | 235 | 1146.0 | 1200 | 599 | 488 | 961 | 4.70 | 72 | 54 | 0.571 | 0 | 0 | 157 | 5 | 2 | 1.47 | ||
| Estes, Shawn | 1997 | NWK | 32 | 198.7 | 203 | 100 | 115 | 143 | 4.53 | 16 | 6 | 0.727 | 0 | 0 | 32 | 6 | 1 | 1.60 |
| Estes, Shawn | 1998 | TOL | 34 | 191.0 | 187 | 113 | 121 | 139 | 5.32 | 7 | 12 | 0.368 | 0 | 0 | 33 | 1 | 0 | 1.61 |
| Estes, Shawn | 2000 | PHX | 2 | 12.0 | 7 | 3 | 6 | 12 | 2.25 | 0 | 0 | #DIV/0! | 0 | 0 | 2 | 0 | 0 | 1.08 |
| Estes, Shawn | 2001 | PHX | 35 | 165.7 | 224 | 121 | 98 | 104 | 6.57 | 9 | 14 | 0.391 | 0 | 0 | 31 | 1 | 0 | 1.94 |
| Estes, Shawn | 2002 | PHI | 21 | 128.7 | 134 | 69 | 50 | 106 | 4.83 | 8 | 7 | 0.533 | 0 | 0 | 21 | 0 | 0 | 1.43 |
| Estes, Shawn | 2002 | CAR | 9 | 49.7 | 58 | 29 | 23 | 23 | 5.26 | 3 | 5 | 0.375 | 0 | 0 | 9 | 0 | 0 | 1.63 |
| CAREER | 133 | 745.7 | 813 | 435 | 413 | 527 | 5.25 | 43 | 44 | 0.494 | 0 | 0 | 128 | 8 | 1 | 1.64 | ||
| Estrada, Marco | 2012 | PHI | 58 | 92.0 | 90 | 53 | 44 | 74 | 5.18 | 4 | 7 | 0.364 | 6 | 3 | 0 | 0 | 0 | 1.46 |
| Estrada, Marco | 2013 | LV | 32 | 183.0 | 195 | 91 | 60 | 193 | 4.48 | 18 | 10 | 0.643 | 0 | 0 | 32 | 0 | 0 | 1.39 |
| Estrada, Marco | 2014 | BR | 22 | 113.0 | 133 | 68 | 31 | 101 | 5.42 | 4 | 11 | 0.267 | 0 | 0 | 19 | 0 | 0 | 1.45 |
| Estrada, Marco | 2014 | ARK | 3 | 19.7 | 16 | 6 | 3 | 14 | 2.75 | 1 | 0 | 1.000 | 0 | 0 | 3 | 0 | 0 | 0.97 |
| CAREER | 115 | 407.7 | 434 | 218 | 138 | 382 | 4.81 | 27 | 28 | 0.491 | 6 | 3 | 54 | 0 | 0 | 1.40 | ||
| Eyre, Scott | 2005 | NWK | 9 | 11.3 | 14 | 9 | 9 | 10 | 7.15 | 1 | 1 | 0.500 | 1 | 1 | 0 | 0 | 0 | 2.03 |
| Eyre, Scott | 2006 | NWK | 55 | 59.0 | 64 | 38 | 30 | 56 | 5.80 | 2 | 3 | 0.400 | 7 | 6 | 0 | 0 | 0 | 1.59 |
| Eyre, Scott | 2010 | NJ | 3 | 6.7 | 6 | 3 | 2 | 4 | 4.05 | 0 | 1 | 0.000 | 0 | 0 | 0 | 0 | 0 | 1.20 |
| CAREER | 67 | 77.0 | 84 | 50 | 41 | 70 | 5.84 | 3 | 5 | 0.375 | 8 | 7 | 0 | 0 | 0 | 1.62 |